A Cure for Alzheimer's Disease
Alzheimer’s disease is one of the greatest challenges in modern medicine, affecting more than 50 million people worldwide. Our goal is simple: to find a cure.
55
Million People Currently Live with Alzheimer's Disease
1
Trillion US Dollars Expended Each Year Worldwide
6
Million New Cases Per Year
80
Million Patients Estimated to have Alzheimer's by 2050

Learn More About Our Mission
Our Research
Our goal is to create a drug that will stop Alzheimer's in it's tracks. We bring together diverse scientific approaches to better understand and treat Alzheimer's disease. Our cross-disciplinary team of scientists combine their expertise to fulfil this mission, from identifying drug targets to synthesising and testing potential therapies.
Computational Chemistry
We take promising theoretical candidates and chemically synthesize and purify dozens of these each week. As part of this work, we have devised and published several novel synthetic procedures.
Synthetic Organic Chemistry
We take promising theoretical candidates and chemically synthesize and purify dozens of these each week. As part of this work, we have devised and published several novel synthetic procedures.
Molecular Biology
Our biologists then use a variety of assays to test the safety of our promising compounds, and whether they work in biological systems. They also work to find the specific proteins and molecules that lead to the degeneration of brain cells and learn how we can stop them from malfunctioning.
Pharmacology
Successful molecules are then tested in multi-cellular living systems to observe how they will be digested and processed by the body. Exceptional drugs will proceed to human trials.
Our Research Interests
Our search for a drug for Alzheimer's Disease takes us into a variety of dynamic research disciplines. Below are some areas of our current research.
Modelling Alzheimer's Disease
Better practical models for better prediction of potential treatment behaviour
The Blood Brain Barrier
Overcoming the BBB so our drugs can reach their targets in the brain

Learn more about our current research projects.
Our Team
From Computational Chemists to Molecular Biologists, meet the people behind our research.
Our Lab and Facilities
Our lab includes diverse experts and trainees from multiple scientific disciplines as well as comprehensive organic chemistry, cellular biology and spectroscopy facilities. Discover the facilities that make our research possible.


Your brain is what makes you, you!
Here's what we're doing to protect it!
Our Latest News
Catch up with some recent updates from our lab
Fighting COVID-19 with Blood Pressure Medications
Early findings from our lab suggest that the widely used diruretic Furosemide may have some value in managing the symptoms […]
How Coffee May Protect Against Alzheimer’s and Parkinson’s
Drinking coffee could possibly protect against developing both AD and PD.
Alzheimer’s Drug One-Step Closer to Reality
Major deal to develop Alzheimer’s drug shows UHN is a world leader in neuroscience research.



